The positive electromeric effect results when the pi electron pair is transferred to the atom to which the attacking agent is attached. The main difference between resonance and mesomeric effect is that resonance occurs due to the interaction between lone electron pairs and bond electron pairs whereas mesomeric effect occurs due to the presence of substituent groups or functional groups. These electronic factors involve organic molecules, most of which are made from a combination of the following six elements: carbon, hydrogen, nitrogen, oxygen, phosphorus, and sulfur (known collectively as CHNOPS). However, inductive effect and mesomeric effect arise due to two different factors. Atoms with a high electronegativity tends to … Key Difference – Inductive Effect vs Mesomeric Effect Inductive effect and mesomeric effect are two types of electronic effects in polyatomic molecules. Mesomeric effect is the effect of substituents or functional groups on chemical compounds. MESOMERIC EFFECT The permanent polarization of a group conjugated with a bond or a set of alternate bonds is transmitted through the electrons of the system, resulting in a different distribution of electrons in the unsaturated chain. Electronic factors that influence organic reactions include the inductive effect, electromeric effect, resonance effects, and hyperconjugation. Inductive effect is the effect caused by the induced electrical charges in atoms of a molecule. This charge induction occurs due to the differences in the electronegativity values of atoms. In contrast, the negative electromeric effect is a result of the transfer of the pi electron pair to the atoms to which the attacking agent is not attached.. What are the Similarities Between Inductive Effect and Electromeric Effect? Main Difference – Inductive Effect vs Resonance Effect.